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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8338d3300d1265affd510118fe332edb0f5fd0c0211a6f4764d6066e7571bd1' 
  AND token = 'T3orTxFFM4uc6hvG+4A5qMwVfz6Fdx3OoRlOcinYizc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}