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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffc5c57af35d01f487ba5e582287c8d18bbf59da4c173ab341699a809838372c' 
  AND token = 'lGBIFlR+6OEOcC13C2V15cAC1RH/jQYfv7bkTXDBfmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}