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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387d90290287a0d98a65821879c52a1e073fb0d03f73d67200122a25940430f4' 
  AND token = '8pDuoQgNZWEs/6mxTUJIo2cbZBU3vK6UwJsaIzsN5fA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}