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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f0900226727ea1b6a56a8fe3baeb892a2b04d477fc262421fb3c3b60b236f8' 
  AND token = 'FKdzC0Hs04ZO7Cy7Ui1phpf35LWsp755MzzPRs8AbaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}