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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0d607e955d23beab77771c70314659104e29b99af67257d4dc078f9081e405' 
  AND token = 'uLGEUaMo2K7wJ4H/O3U0qpq03OsOXNRoeZa2tJ98/h4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}