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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca72d46c88973a2b61903b45f80b30fc1d042069a458303f3c15fdda375c7214' 
  AND token = 'hTgipFoFe1gCszAAFKDMfZ2u3rtKTwpaZF+k+8dRzp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}