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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d879873f42709b0e94d159e0d83a376edde8e133597fdfed3617d1015af0d7d' 
  AND token = '5+5ssoHROp5EmHpIo+EOg1gqAiA4X1LpxEE9NXsiXxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}