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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41250bfe2040ac6ebb23441834d64d9bbd9310b6e9f49f5a383ce24539e6ecf' 
  AND token = 'S/6sEIX7a8cvF9h3rJpR2ydbD9rOuJU5kjo5xQ+SGeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}