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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19d7d2233b40ca7078ea44c47d62f911c3fa2fabd5226e7a94145d8d861c0d48' 
  AND token = 'EWGsjHWQMawvTCaY7plk3JrtFHb5g/JfwWrBL4kCQs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}