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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8acecbba7b4adf5ce1b3cbe973f343d3b0def523848f8a3cdc4a8588c2935ad2' 
  AND token = 'C7ri3fZnISQVnAXY0DwpFkZ+L5AcV9oOfy34gCnLAD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}