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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3213642a8fe75c387f7b5ae853274e58a3a2b30a042a02476089abf11f31eff9' 
  AND token = '4uUR0bjYSS0oHSfi0PZuLQsqBa9/4LjqLHuAg99AiXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}