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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b7a931c87d93dec9488242591f973d2b381943efe3017a9b2f296561e7bbbc2' 
  AND token = 'hRyyiRUlV14gI3yrbI0W4vxezv/KDqoO1w3IyoBLs10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}