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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e5365ba54cdbb9ce21b7fc51d9d45b6d249eb9318317bb6a19c6c67b42b995' 
  AND token = 'KoJ8fxOZh49qMdkpfjfk7yyahnaNbWJKDUwmoxt/8qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}