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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ee40668e58f392021e4f70cb62d27d87322ce4764e8f028ff3e93a730aa860f' 
  AND token = '8qxQrtTCjmxkp6eOO0iuRUISaa7n9/Ipao3WyfiAIpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}