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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8200b5cfae3d43169e1b7ac8ed2e130ce9a1e256357244a2630816a90feaf108' 
  AND token = 'Mg2rF7dOaO3VAJJnrK6oQWOTL/sSc0zdEg87vCi9Vpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}