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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05724e7019357fd14cdb8a69ee40b240f2b1220b17f054f38027954d16acb35' 
  AND token = 'AvS6XxNPf+kpaP0qGO1Ss0TE/8YEKvohnVo6xsOLaF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}