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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e37c09f90455e509b1b39b85d9d9c5e46cb55dbb758b1c545632544a549d59f' 
  AND token = 'gyx9qjMwstPXLg0okm9LsGenc95XCBb3tEvYbHKA4nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}