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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500ebe715b8b2029c86fdaf2dccda451886544685e4fa7d2ba2f44d7b3d00082' 
  AND token = '/lTiIBjm4yKZbj2i93XHeNjy3w03jLxb5+ADa3pfBtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}