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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bd846241b718e25469271511807aaf30170b197ae2f15b36c51ba340bb94003' 
  AND token = 'pmrYpWAoTxLe6GflpGERl8m3vGqZhhujduLhSkkQ2RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}