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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19dd8c298c8e73b6b664fad4db17b82c492841685320a9e450ea4097fe25cfa' 
  AND token = 'Z8YYS7xE1RuF+TsYHqNQ4+Euk1YZnF/xaMs8nRMl5p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}