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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5319bda650e29be1cf4f3feb5c7f0ea0a85a9c314beb338738a74483b09e07f2' 
  AND token = '3GCw6Qn/smHQikEsitLozk2nid66JWsZ0zzeVnlvztY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}