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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433e9e08e99aef6d39a18f8a0517bdef5745578967d78fcb048a6b684fa72c55' 
  AND token = 'B7JWBmOdth1mM1HFAwbtSJcFru0gdEg9S2yWi15nC34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}