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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da8b8183f393c75e453ffcca1be0346b87d5faecc4d4530632cd749d038b6ae1' 
  AND token = 'MLAK/X2y3jO6mYN7NaWtKx0LgmW2WK8xEa7LuWi1ZGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}