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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21d4f440b847eb8670a5901976be7295eae6d1a15e6cc18f722842aafc87b41' 
  AND token = 'iB0OpZOgNoC9Ov4We41PWXMnxu9+8bjYzgEVk4ZheEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}