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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c03ce022cf3d3bec3572cb4f44b21fd9e6aa7636e2b1fc729508d1ab89c6bd0' 
  AND token = 'S4NpisqPxQjoIZhO6JJf2FZ602QIksbmtpDSHFRgHRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}