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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6d72ddae34d0895a08be8d054c090a7c8a190431ae54f1a0a51b38e48e5cd5' 
  AND token = 'lr9eOeGWMb3xYWt+L/PvujDgiQToyAOpcWev85j/RfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}