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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f5d5e3fdf96a5bf607fffe25dc5859d4d5357d06017761d610e3617f201286' 
  AND token = '5JTtYrzxCh/GVdH3eT0m5gCa2HsR6iRftfq7apDvN+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}