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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f61e1644a241b42b5f9ae39f50782cb9553689da45911677bc99a0a34edae760' 
  AND token = 'ZK9C7G0DaeAPUB9SjjEFnWXSIZR5Ty3CMdzSyXPOEhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}