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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2800a4b2d7c13b979b1d645e238fb80650cfb3e09438bb19358dd9e9ca54a4f4' 
  AND token = 'K5Vq+5Xm/VoMQTikL8K6js/owQnl75jfDoCBy1ETc7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}