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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c19a77b32d49be878f652918613dad5c1a160bc3849b3b6f1026e5f180459d' 
  AND token = 'IlGDcr+rcWfMo278g6VjjjGXqRT3D8LFfNLJAMU8P5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}