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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '181a918f89961e1e8939da0e12a7e4a9e92cff010ecf59b16ba0976c037f3afc' 
  AND token = 'f2cbhg2laSTeMSrhhX6ho58H6IduH4aHa8s3WjZN6Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}