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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73ce8d9c4ea42039cc455f207aff06b7b53be807ca890ed38079bb85bf78215c' 
  AND token = '1BlfNUtFrY23r4tet48VbylUhYuIBdUK1gE/BpoyEMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}