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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1286a48c4257eb20e6233e74bd3449d5994fc4b87adb933cd22d2576d5ec0f4' 
  AND token = '3RO3MXNcURCktJ5oT9LfE/+7aRMVEpBuoQbpAlvw5oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}