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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c9449d3c20362646a112d39d3dc5259f592a503b6dc78f531022efe4f96384c' 
  AND token = 'fUPkcLuRtsLus/9YGaGHOFyFaXpXssKIcUyWHKjeiNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}