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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7af6c42a78e1235e586938842a0197087f3d591da858c93c08ea5e95bf70a457' 
  AND token = 'RRRo5olIsgDzzoCvUcu901owsuD9q05BVO8GCTvAzkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}