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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422aedea9feef902fea8bf58459f34d1ad9d1af2824140ab7ac811b649ea4f3d' 
  AND token = 'qBIfT5wbPpu0+19FAnJI5iMXUDrwr6iMUHaIrUUYSXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}