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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220284e4731d8c64e186ac5d47ae14b939d225bc701b33e0916e9b45a8a059a3' 
  AND token = 'mjQUaH9rSZb8KST3IFMvBteaIteOryaBDOrXLezigWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}