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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e42fc73d19ad5d8e7abafefb988a8dd74868737bdb6dc8e5c971d332daa1c46' 
  AND token = 'BUQ8E0f17xB/drO6dzjr7SKcQEXXyq9GOtCFr2cUi8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}