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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4af8ea2ba0b3d94b47e5780ecec272fc07d5489ea11b8d7da2dffff36400a817' 
  AND token = 'uBe42hALInbLKhpz441QIdyLrfqMbJUrlV/vFQszb4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}