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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc25c89d18ec55cfb4d0e8ed2c4a2135411618bf195de7f9ea912ce88ecdddbc' 
  AND token = 'nnvRU8+/YmppR/wdgIQCPV+kWU30slRND2lr7BxPb+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}