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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc1d11129be35d2ea01da1497b6f43e9a8c439f54cc5a21f41d6a78e7b1189a' 
  AND token = '77vJGkL+zIs55oN6l+gvOuPfCX+wfx4BNLAtn0W8d0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}