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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f722e8a53a852f31185c6f4762ea11e896ec4c5c2f01da0a5d7ccfef07e7af' 
  AND token = 'C7OtLF9fT79kVjQ/C+mo2N8GzyH8K9ZBrPvm3cCWfhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}