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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051b41efcac82940c3f1aca4a019196159c5c44b63ed7902be88ff3c7b07f2c1' 
  AND token = '1ZsgatWdf1AxUMq+ahW4odmK57MkE/jKHi5OlOpG0Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}