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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781a0fd431c464a0399e23c88de8375b822985b29ee0df9f41328c028cca93ff' 
  AND token = '+CVpjBEz+kgGLrUSftxn1z6L1cH2AilZrVUxULXO+vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}