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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a2e661e873aa7502d0f4f625d8b4e304e5c1473a3a146a75f644b49b2448dbf' 
  AND token = 'EeDfbDmKdWffSJLLzQmpvz/ByPqNw1Ja5BizwpnqoxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}