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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80de7f377fcb2bda693334b8e2c697da4210f7a6d6d6eccd859c4ba62f37b483' 
  AND token = 'fjugP+S+DK/+ENM0hsa7sFpc8cV16qTEahWmd/neApQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}