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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c48b9733d7f8a2d453a1d52c97c56db178cb7adf08c399ddda39a158a4d6b27' 
  AND token = 'AaakQR4JkVtOWn57wMv/GESPsrvwF3AK4BrTL7CL0g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}