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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f1d058b5c3c8147387552a29da1f918f2bc1d52fef4e9be70990550e9cb25b3' 
  AND token = 'PKOUwkIY6+Fi4bmBVaytY+jMTWc8ySxDoHY+OZ5PvBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}