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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd08f1308e6c36430ac49e10791231dbea420689353800042b3c663ede275b067' 
  AND token = 'dm/Q6bAKYqixzSt2AyxX9YNvzP4ZaLwX7UNnuEKVLms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}