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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aebb07bd661f215a1bea37e755a4aabac70df5e712249ff5992e27b022c0255a' 
  AND token = 'fTNFFI9DhVcwpmipRS/edCq88JmpPyNx7fCDdaEmSb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}